X chromosome

noun

: a sex chromosome that usually occurs paired in each female cell and single in each male cell in species in which the male typically has two unlike sex chromosomes compare y chromosome

Examples of X chromosome in a Sentence

Recent Examples on the Web
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This signaled that the mutation was somewhere on the X chromosome, since females have two of those, and presumably one lacked the killer mutation. Beth Mole, ArsTechnica, 6 Oct. 2025 Aicardi syndrome is an extremely rare condition that results from a mutation on the X chromosome. Erika Edwards, NBC news, 4 Oct. 2025 Some research suggests that having two X chromosomes may protect females from harmful mutations, offering a survival advantage. Maria Azzurra Volpe, MSNBC Newsweek, 2 Oct. 2025 Some research suggests that females might be protected from certain harmful genetic mutations because of the two X chromosomes. Laura Baisas, Popular Science, 1 Oct. 2025 See All Example Sentences for X chromosome

Word History

First Known Use

1911, in the meaning defined above

Time Traveler
The first known use of X chromosome was in 1911

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Cite this Entry

“X chromosome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/X%20chromosome. Accessed 18 Oct. 2025.

Kids Definition

X chromosome

noun
: a sex chromosome that is associated with femaleness and usually occurs paired in each female cell and single in each male cell in organisms (as human beings) in which the male normally has two unlike sex chromosomes compare y chromosome

Medical Definition

X chromosome

noun
: a sex chromosome that usually occurs paired in each female cell and single in each male cell in species in which the male typically has two unlike sex chromosomes compare y chromosome

More from Merriam-Webster on X chromosome

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